Fibroblasts - Histology, Wound Healing, and Macrophages/Myofibroblasts
2:39
Fibroblasts - Histology, Wound Healing, and Macrophages/Myofibroblasts
Mar 16, 2020
microscopemaster.com
Wound Contraction ✨Myofibroblast: Specialized fibroblast with contractile cytoplasmic microfilaments and distinct cellular adhesion structures (desmosomes and maculae adherens) ⚠️Dispersed throughout granulating wound; act in concert to contract entire wound bed ⚠️Appear on day 3; maximal on days 10-21; disappear as contraction is complete ⚠️Less contraction when more dermis is present in wound, just as full-thickness skin grafts have less secondary contraction than split-thickness grafts ❤️TIP:
2:22
Wound Contraction ✨Myofibroblast: Specialized fibroblast with contractile cytoplasmic microfilaments and distinct cellular adhesion structures (desmosomes and maculae adherens) ⚠️Dispersed throughout granulating wound; act in concert to contract entire wound bed ⚠️Appear on day 3; maximal on days 10-21; disappear as contraction is complete ⚠️Less contraction when more dermis is present in wound, just as full-thickness skin grafts have less secondary contraction than split-thickness grafts ❤️TIP:
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