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The juxtaglomerular apparatus (JGA) is a specialized microscopic structure located where the distal convoluted tubule (DCT) meets the afferent arteriole of the same nephron. Its primary role is to maintain blood pressure, glomerular filtration rate (GFR), and sodium balance through tightly coordinated sensing and hormonal release. The JGA is made up of three key components: - Macula densa — A cluster of epithelial cells in the DCT that detect changes in sodium chloride concentration in the filtr
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