Fabry disease is a rare genetic condition in which you don’t produce enough healthy versions of an enzyme called alpha-galactosidase A (alpha-GAL). This enzyme breaks down …

Fabry disease is caused by a mutation in the DNA sequence of the GLA gene. A person who inherits this mutation does not have enough of a functioning enzyme known as alpha …

Aug 5, 2002 · Fabry disease is the most common of the lysosomal storage disorders and results from deficient activity of the enzyme alpha-galactosidase A (α-Gal A), leading to progressive …

Nov 28, 2024 · WebMD looks at the causes, symptoms, and treatment of Fabry disease, an inherited condition that brings on a variety of symptoms, including pain in the hands and feet.

Jun 6, 2019 · Fabry disease is a rare inherited disorder of glycosphingolipid (fat) metabolism resulting from the absent or markedly deficient activity of the lysosomal enzyme, α …

Fabry disease is an inherited disorder that results from the buildup of a type of fat, called globotriaosylceramide, in the body's cells. Beginning in childhood, this buildup causes signs …

Fabry's disease is an X-linked lysosomal storage disorder caused by abnormalities in the GLA gene, which leads to a deficiency in α-galactosidase A. The consequent abnormal …

Oct 14, 2024 · Learn more about Fabry disease, including its symptoms, what causes it, and how it's treated.

While the age of onset, progression, severity, and health implications can vary significantly, the symptoms listed here are very common for many individuals with Fabry disease.

Aug 30, 2025 · Fabry disease, also known as Anderson-Fabry disease, is a multisystem disorder resulting from an X-linked inborn error of metabolism and is a lysosomal storage disorder.