TLR4 recognizes bacterial-derived lipopolysaccharides and activates IRF3 via the adapter protein TRIF, contributing to the induction of type I IFN genes. Within endosomes, TLR3, TLR7, and TLR9 ...

Adam Morgan’s riveting and indispensable first book, “A Danger to the Minds of Young Girls: Margaret C. Anderson, Book Bans, and the Fight to Modernize Literature,” is a revelatory introduction to ...

ST. PAUL — Minnesota enters the new year with a range of new laws from the 2025 session — affecting health care, voting, labor standards and hunting regulations — taking effect alongside the ...

NOISES OFF by Michael Frayn is an audience favorite comedy that premiered in 1982, with a Broadway revival in 2015. As actors prepare to tour their new stage production, they struggle to learn their ...

After Joey Zwillinger stepped down as CEO of Allbirds in March 2024, he took three months off—mainly because his wife Liz said she’d divorce him if he jumped into another venture. He had run the ...

The growing awareness of the value among parents wanting to develop and inspire their child’s interests is not only driving more companies to develop educational products but pushing sales. According ...

“Give us a clock tick” is an expression uttered several times in “Wicked: For Good.” But Jon M. Chu’s two-part musical has asked for quite a bit more than that. Together, the two halves of this ...

JACKSON TWP. − Pioneer Coffee Roasters, with locations at 7924 Hills and Dales Road NW in Jackson Township and 60 Lincolnview Drive in Dalton, has earned international medals at The Golden Bean, an ...

Going into “Wicked” last year, my main concern was the seemingly bloated running time of the first of two stage-to-screen adaptations of the smash Broadway musical. The first film clocked in at ...

NEW YORK, Nov. 18, 2025 /PRNewswire/ -- Results from The Princeton Review®'s second annual Campus Mental Health Survey—a project the education services company conducts in partnership with the ...

As Honda Powersports enters Grasso’s Garage for the first time, we recognize why consumers have been addicted to the brand for years. Enter the 2025 Honda Pioneer 1000-5 Trail Special Edition, a ...