Background Hospitalisations represent major clinical events in cirrhosis, yet prediction based on clinical variables alone remains limited. Objective Given the role of the gut microbiome in disease ...
Eosinophilic gastritis (EoG) is a rare, chronic disease characterised by pathological eosinophilia of the stomach and ...
Following publication of the Rome V diagnostic criteria for disorders of gut–brain interaction (DGBI) earlier this year,1 the findings of the updated global epidemiology survey of DGBI in this issue ...
Background Translating microbiome correlations into robust predictive features for complex gut disorders remains elusive, ...
Background Engineered bacterial therapeutics represent a promising strategy for sustained intestinal delivery of therapeutic molecules, but their efficacy is limited by inefficient colonisation, ...
Background Programmed death ligand 1 (PD-L1) blockade offers new therapeutic options for oesophageal squamous cell carcinoma (ESCC); however, the underlying mechanisms and associated biomarkers that ...
Recent work in Gut has highlighted multi-kingdom interactions between gut bacteria and bacteriophage (‘phage’) as contributors to Crohn’s disease.1 Whether similar alterations characterise colorectal ...
Background Neuroendocrine carcinomas (NECs) comprise a highly heterogeneous group of lethal malignancies arising from diverse anatomical sites. Objective We aimed to provide a functional blueprint for ...
Risk stratification in compensated advanced chronic liver disease has traditionally been based on the identification of clinically significant portal hypertension (CSPH), defined as a hepatic venous ...
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