12 min read | Unique research highlights an overlooked mental health disparity among Indigenous North American people with HD – and the need for care grounded in trust, community partnership, and ...
In plain language. Written by scientists. CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New research finds that blocking cells from ...
In plain language. Written by scientists. Skyhawk shared data at the 15 month mark for SKY-0515 treatment in people with HD in their Phase 1/2 trial. The drug is working as designed and there are some ...
In plain language. Written by scientists. Roche gave an update this week about GENERATION HD2, testing the HTT-lowering drug tominersen in people with HD. The trial is continuing, but only the higher ...
In plain language. Written by scientists. ⏱️6 min read | Most people with HD report sleep problems, & new research suggests sleep quality is linked to many aspects of living with the disease.
HDBuzz has been following SKY-0515 since the first results from its Phase 1 study were announced in 2024. Early testing in ...
In plain language. Written by scientists. ⏱️8 min read | What if nutrition is one of the warning lights we should be checking earlier in Huntington’s disease? New research suggests simple nutrition ...
Huntington’s disease (HD) is caused by an expansion of a short DNA sequence — the letters C-A-G — located in the very first part of the HTTHTT one abbreviation for the gene that causes Huntington’s ...
Although eyesight itself is usually preserved as symptoms progress, Huntington’s disease (HD) can affect visual cognition. This means it can affect how the brain recognizes, understands, and responds ...
In plain language. Written by scientists. Heart health has been linked to lower levels of NfL, a key biomarker of brain cell damage in Huntington’s disease. This suggests heart-healthy habits – like ...
In plain language. Written by scientists. Transplanting healthy human glial cells into HD mouse brains improved movement, memory, and survival. Even more strikingly, the glia coaxed diseased neurons ...