Screening ionisable lipids with a gene-editor-sized RNA identified LC-1, an LNP component that retained potency as cargo ...
Incyte will share updated clinical single-cell data characterizing its calreticulin-targeted therapy for myeloproliferative ...
Researchers in Germany have identified a SOX9-responsive regulatory route to IRF6, a major orofacial-cleft risk gene, in ...
Sofi-cel is an allogeneic, off-the-shelf, CD7-targeted CAR-T cell therapy being developed for T-cell cancers. Allotera uses ...
A mutation-agnostic CRISPR-Cas strategy that inserts a functional rhodopsin coding sequence into the human RHO locus has ...
Base editing offers far more versatility than its name implies. The technique was initially developed to correct ...
Ole Bock moderated two sessions at the Chinese Society of Cell & Gene Therapy Annual Meeting in Beijing, and CMN received the ...
CMN founder Jens-Ole Bock will moderate a panel discussion at CSGCT 2026 in Beijing on 20 September on the question that now defines the field: with the first in vivo CRISPR therapy under FDA priority ...
A rare visit to a pharmaceutical R&D facility offers insight into how drug discovery, CRISPR technologies and clinical translation are carried out in practice. The article highlights why greater ...
Rationally engineered chimeric attachment sites raise the efficiency with which the serine integrase Bxb1 inserts large DNA cassettes into targeted loci in both human cells and rice. Paired with an ...
A mutation-agnostic CRISPR-Cas strategy that inserts a functional rhodopsin coding sequence into the human RHO locus has preserved retinal structure,... Base editing expands its scope through advances ...
A six-year-old girl died after receiving an experimental CRISPR-Cas base-editing treatment for a nonfatal neurodevelopmental disorder in China. The fatal immune reaction followed preclinical safety ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results