Molecular changes involving inflammation and protein processing were detected before ALS-like symptoms appeared in a SOD1 mouse model. Activity of genes including SOD1 and Il33 differed in the mouse ...

But what about all our plans?” I asked my husband right after receiving my ALS diagnosis in 2024. “We’ve got places to go, ...

Acelot has dosed the first healthy volunteer in a Phase 1a clinical trial testing ACE-2223, its investigational oral treatment candidate designed to target aggregated TDP-43 in people with amyotrophic ...

Geneuro received a European patent for GNK-301, an antibody targeting K Env, with Phase 1 trials planned for the second half of 2027.

Paradromics’ investigational Connexus brain-computer interface (BCI) enabled a woman with a progressive motor neuron disease to generate her own words in real time, answer open-ended questions, and ...

It’s a schtick we repeat whenever he needs to reorder something he buys in bulk, like gauze pads, deodorant, or gloves. He always feigns disappointment when we run out of something. “So irritating,” ...

Mindy Henderson has spent much of her life challenging the limits others have placed on her. When she was diagnosed with ...

In 1980, a local hospital hired me to launch their brand-new wellness department. I knew it would be an uphill battle. Back ...

Five Canadian college students personally affected by ALS were named recipients of the Kevin Daly Bursary, an award for their ALS advocacy. Financial programs like student bursaries help alleviate ...

Filmmaker and University of Virginia graduate Chris Farina had the idea for a documentary about death and dying about 10 ...

Requests for a medically assisted death in ALS appear to be tied to individual preferences rather than disease severity, a ...

Many well-intentioned people romanticize caregiving, perhaps out of compassion or even admiration of one person caring for ...