Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 51 (December 19, 2017), pp. 13424-13429 (6 pages) Unlike most macromolecules that are homogeneously ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A molecular framework of how ...
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