Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...
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Biochemist Katalin Karikó and immunologist Drew Weissman won the Nobel Prize in Physiology or Medicine Monday for their foundational research showing that chemical modifications to the molecular ...
Marissa Russo is a former STAT intern supported by the AAAS Mass Media Science & Engineering Fellowship. An oral capsule can efficiently deliver liquid mRNA therapy directly to the gut, a possible new ...
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