After a good showing in Week 1, the goodwill the Arizona Cardinals got has been forgotten. After their 31-7 home loss to the Seattle Seahawks on Sunday, they plummeted in the latest NFL power rankings from NFL.

The Arizona Cardinals are now 1-1 on the 2026 season following a 31-7 loss to the Seattle Seahawks.A flat offensive performance headlined by Jacoby Brissett’s sub-100 yard passing showing isn’t an ideal start point for inter-divisional play.

San Francisco 49ers vs Arizona Cardinals odds for NFL Week 3 game betting, including point spread, moneyline, over/under for Sunday, Sept. 27, 2026.

The Arizona Cardinals are not expected to be good in 2026. They are projected to have the fewest wins this coming season. However, after the offense looked productive in the preseason, they open the season rising in new NFL power rankings to start the season from NFL.

Check out all the ways to watch, listen and live stream the Arizona Cardinals against the San Francisco 49ers on September 27, 2026

The Arizona Cardinals show potential but face challenges after a tough loss to the Seattle Seahawks. Their home losing streak extends to eight games after a 31-7 defeat.

Toia is a 6-2, 340-pound defensive tackle who was drafted by the Dallas Cowboys last year in the seventh round. He played five games for them. These tryouts suggest that perhaps there is something wrong with outside linebacker Eku Leota and that perhaps Lopez or Billings are banged up again.

Two games into the Mike LaFleur era, the Arizona Cardinals flashed real promise — but a growing injury list and quiet stars leave plenty of questions unanswered