An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy. This subtype grows even ...

A biobank for pediatric kidney tumors plays a key role in identifying hereditary causes of Wilms tumors. New insights gained with its help enable better risk assessment for affected families and could ...

Xiang Chen, PhD, Department of Computational Biology and Andrew Murphy, MD, Department of Surgery are co-corresponding authors of a study that sheds light on predisposition to bilateral Wilms tumor.

Children with bilateral Wilms tumor have a tumor in each of their kidneys - a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St.

Diffuse anaplasia, a Wilms tumor subtype with a poor prognosis, possesses mutations that enable it to grow despite a high level of DNA damage, making it resistant to chemotherapy. An international ...

A research team at the University of Würzburg has gained new insights into the development of kidney tumors in young children. These enable a better risk assessment and could form the basis for ...