RNA is a fundamental molecule of life that plays diverse structural, functional, and regulatory roles in all organisms and pathogenic viruses. In recent years, the discovery of new classes of RNA ...

Researchers developed the novel and publicly available computational tool Millefy to visualize heterogeneity in RNA biology between single cells. Using mouse embryonic stem cells and cells from triple ...

RNA molecules play critical roles in regulating gene expression. Perturbation of RNA processing and metabolism underlies a wide range of human diseases. RNA research in the Department of Genetics and ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

In recent decades, significant advances in science and technology have greatly enhanced understanding of the many biological molecules that contribute to life’s complexity. RNA is one such molecule ...

Synthetic biology strives to achieve robust control of biological processes in order to create designer organisms for a variety of industrial, diagnostic, and therapeutic applications. Researchers ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

This activity was supported by contracts between the National Academy of Sciences, National Institutes of Health, and The Warren Alpert Foundation. Any opinions, findings, conclusions, or ...

Developing tools for precise control of biological processes has been one of the main pillars of the now mature field of synthetic biology. These scientific tools borrow principles from a multitude of ...