Colossal Biosciences will sequence and cryopreserve genomes for all 2,300+ US endangered species in partnership with Fish and ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Researchers have identified "DNA switches" that become active as honeybee larvae grow into worker bees, offering new insight ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

Gene mapping is the discipline devoted to determining the linear order and chromosomal coordinates of genes and other genomic elements. Traditional genetic mapping employs linkage analysis, in which ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D.

Current approaches to mapping fork progression in the human genome suffer from drastically low throughput. Here, we introduce ForkML, a nanopore sequencing-based method automatically positioning ...

DNA's double helix has long stood as the symbol of life's code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

Spoorti Gandhadmath carefully placed 3.5-inch (8.9-centimeter) pots on a shelf in a growth chamber. Within seven days of ...

A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other regulatory proteins that control gene activity, according to a study led by ...