Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

Distant metastasis and recurrence remain major obstacles limiting the long-term efficacy of immunotherapy for solid tumors, particularly in highly aggressive cancers, such as malignant melanoma.

Novel research led by Brazilian scientists describes the immune system's reactions in detail in the first living patient to ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. The work stems ...

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. The work stems ...

The relationship between inflammation and cancer represents one of the central paradoxes in modern tumor immunology. On one hand, chronic inflammation is a ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...