Scientists have gained tremendous control over the genome with CRISPR editing systems, that use a guide RNA molecule to ...

Left panels: Atomic Force Microscopy images show how circular DNA can shift from a relaxed shape into a tightly twisted form, and how the gene-editing protein Cas9 binds to this coiled DNA (Credit: ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules. DNA is a molecule found in just about every living cell. Because ...

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules. DNA is a molecule found in just about every living cell. Because ...

At the core of each of our cells, the DNA molecule is constantly changing its configuration. When it twists or unfolds, it determines which genes are activated at each moment. "We have shown that the ...

Using high-resolution cryo-electron microscopy (cryo-em), researchers from Durham University, Jagiellonian University, and the John Innes Centre uncovered unprecedented detail of gyrase’s action on ...

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a precision tool, but is not perfect, and misplaced DNA edits can compromise ...