Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

DNA double-strand breaks (DSBs) represent one of the most deleterious forms of genetic damage, arising naturally during cellular replication or as a result of exposure to ionising radiation. The ...

A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

A new study from the Max Planck Institute for Evolutionary Anthropology examined how > 2,000 clinically approved drugs affect DNA repair and CRISPR genome editing.

Scientists have long thought that grey hair may be linked to emotional stress. But while that connection feels pretty ...

Broken String Biosciences launched an early access program (EAP) through which select developers of gene edited therapeutics will be able to use Broken String’s INDUCE-seq ® technology in their own ...

Discover how prime editing is redefining the future of medicine by offering highly precise, safe, and versatile DNA corrections, bringing hope for more effective treatments for genetic diseases while ...

Like base editing, prime editing offers a safer way to genome editing by relying on a nickase enzyme that “nicks” one DNA strand at a time, rather than cutting both simultaneously. Then, with the ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most genetic medicine uses viruses or double-stranded DNA to deliver genetic ...